January 10, 2024
[Press Release] Breakthrough in Designing Complicated All-α Protein Structures
The researcher group in which Koyo SAKUMA, SOKENDAI graduate of School of Physical Sciences, Department of Structural Molecular Science in 2021 participates issued a Press Release.
A team of researchers has developed an innovative method to design complicated all-α proteins, characterized by their non-uniformly arranged α-helices as seen in hemoglobin. Employing their novel approach, the team successfully created five unique all-α protein structures, each distinguished by their complicated arrangements of α-helices. This capability holds immense potential in designing functional proteins.
This research has been published in the journal “Nature Structural and Molecular Biology” on January 4, 2024.
For more information of the press release, please refer to the following.
- Title of Thesis：“Design of complicated all-α protein structures” (a Group of Nobuyasu KOGA)
- Original Publication： Nature Structural and Molecular Biology
- DOI：10.1038/s41594-023-01147-9