[Press Release] Human cytokine equipped with abiotic multinuclear metal center exhibits intrinsic and extrinsic functions
Designer enzyme Structural equivalence is demonstrated through the comparison of a synthetic multinuclear metal complex (left) versus the designer enzyme in this report (right). (CREDIT: Yasunori Okamoto USAGE RESTRICTIONS: Author permission required for redistribution. LICENSE: Original content)
Release Summary
Japanese researchers have developed a human cytokine-based designer enzyme. Relying on their rational design workflow, they demonstrated that proteins can serve as ligands with the same precision as synthetic organic ligands. The resulting designer enzyme maintains its original biological functions while gaining new catalytic abilities.